Soft Tissue Surgical

Surgicoll-Mesh®

Soft Tissue Surgical

Implantable, bioresorbable, tissue regenerative sterile Type-I Collagen Acellular Dermal Matrix designed for reconstructive surgery, chronic wounds, diabetic ulcers, burns and soft tissue repair.

Surgicoll-Mesh product box

Third Degree Burn

Innovative Technology Product For Treatment of Third Degree Burn

A young adult male with severe electrical burn injuries subsequently developed a pressure sore ulcer. Following wound debridement in February–March 2020, Surgicoll-Mesh® was applied, resulting in rapid granulation tissue formation. The patient experienced effective pain relief from the day of application and was able to walk comfortably by Day 7.

Before Surgery

Electric burn victim with bedsore resulting in Chronic Ulcer
Day-0

Day 1

Biological, Biocompatible Collagen product applied
Day-1

Day 3

Shows uplift of healthy granulation soft tissues around vertebral spinous processes
Day-4

Day 3

Significant wound healing
Day-7

Technical reasons for the success of Surgicoll-Mesh®:

Surgicoll-Mesh® is highly bio-active due to its high purity of Type-I Collagen which is phosphorylated to provide relevant tissue regeneration along with maximum wound healing benefits.

Its clinical effectiveness is evidenced through the infiltration of blood capillaries into the Surgicoll-Mesh® matrix within 4 to 5 days after application. As a result, Surgicoll-Mesh® heals wounds significantly faster (at least 60%) than most other advanced tissue repair products in the market.

Surgicoll-Mesh® in the Management of Electric Burn Wounds

Video thumbnail

Courtesy of Dr.V.Rama Devi, Head, Department of Plastic & Burn Surgery,
Kilpauk Medical College and Hospital, Chennai, India.

Trauma Wound

Before Surgery

Before Treatment

Day 3

Placement of Surgicoll-Mesh

Day 3

Healed Wound - Day 30

Day 3

Completely Healed Ulcer
Day 45

Courtesy of Dr. Dhanikachalam, MCh, Plastic Surgeon Chennai National Hospital

Diabetic Ulcer

Surgicoll-Mesh® offers an innovative nanotechnological approach for the faster healing of Diabetic Foot Ulcers.

Case 1

Before Surgery

Post-traumatic chronic ulcer with necrotized 4th toe

Day 1

Debrided Wound – Day 0

Day 3

Application of Surgicoll-Mesh

Day 1

31 Days Post Application

Case 2

Day 1

Chronic diabetic ulcer with maggots – 75 yrs. old pt

Day 1

Surgicoll-Mesh® Application following debridement

Day 1

5 Days Post Application

Day 1

Healed ulcer - Day 30

Case 3

Before Surgery

Initial ulcer presentation

Day 1

Early wound healing - Day 5

Day 1

Progressive wound closure
Day 14

Day 1

Complete wound healing
Day 21

Cases 1 to 3 Courtesy of Dr. Dhanikachalam, MCh, Plastic Surgeon Chennai National Hospital

Case 4 - Leg Ulcer

Day 1

Full loss of initial graft

Day 1

After Surgicoll-Mesh® application

Day 1

Upon graft application on Day 9, by Day 21 shows 100% graft take

Day 1

Stable & pliable graft at 3 months follow up

Diabetic Foot Ulcers (DFUs) are a major healthcare challenge due to their chronic nature, high recurrence rate, and the substantial morbidity they impose. Effective treatment remains limited, which underscores the need for advanced wound care approaches such as High Purity Type-I Collagen-based Acellular Dermal Matrix, Surgicoll-Mesh.

Treatment Options for DFU

Normal materials that are used to cover an ulcer:

  1. Non-biological synthetic polymeric sheets and sponges
  2. Cotton gauze
  3. Vaseline

These materials can protect the wound by acting as a wound covering and may also absorb wound exudate. However, when non-biological scaffold materials are used, the cells involved in the wound-healing process may not interact optimally with these materials.

Consequently, this may unnecessarily delay the wound-healing process, as exudation may continue until the cells adapt to and become comfortable with their surrounding environment.

On the other hand, biological products such as Surgicoll-Mesh® may provide better outcomes. However, it is important to note that not all biological materials are the same. An advanced biological acellular dermal matrix such as Surgicoll-Mesh® is designed to support the wound environment without disturbing the cells on the wound surface that are actively involved in the tissue-granulation process.

Soft Tissue Surgical & Podiatry:

Surgicoll-Mesh® in the Treatment of Malignant Melanoma and Chronic Ulcers

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How Surgicoll-Mesh® Heals DFU Faster

1

Apply Surgicoll-Mesh®

Uncross-linked biocompatible Collagen tightly applied over the wound surface.

2

Glucose Absorption

The Collagen matrix osmotically pulls excess glucose from the hyperglycaemic wound bed.

3

Glycosylation Reduced

With less glucose, newly formed Collagen fibrils avoid glycosylation and can be matured by lysyl oxidase.

4

Normal Wound Healing

Matured cross-linked Collagen enables the diabetic wound to heal mirroring normal wound repair.

Reconstructive Surgery

Surgicoll-Mesh® offers clear advantages over synthetic and other Collagen products for Reconstructive surgeries. It acts as a scaffold that can be naturally and progressively integrated, remodeled and eventually replaced by functional host tissue

Hand Reconstructive Surgery

Before Surgery

Hand deformation before surgery.

Day 1

Post-contracture release, bare bones and tendons are seen

Packing of joint spaces with the Product

Packing of joint spaces with the Product

Post-operative day 7 shows 90% graft take

Post-operative day 7 shows 90% graft take

Hypertrophic Scar

Before Surgery
Day-0
Day 1
Day-1 Surgical excision of scar
Day 3
Post-Op Day-12
Day 3
After 10 months
Efficacy of Surgicoll-Mesh® is proven by formation of new blood capillaries within 4 to 5 days which results in remarkable healing of the wound!
Understanding of the causes for Diabetic Foot Ulcers
Commonly recognized concepts of DFU

1. Nerve Damage

Damage to the nerve by increased level of glucose in blood may result in loss of sensation and the inability to feel any pain or pressure.

2. Poor Circulation

High blood glucose levels thicken the arteries and narrow its blood vessels, restricting the delivery of the blood and oxygen needed to support the body's natural healing abilities.

3. Infection

Suppressed immune system may facilitate pathogen proliferation eventually leading to an infection like non-healing diabetic ulcer.

4. Immune Suppression

Diabetes may suppress the immune system that could impair the body's ability to fight-off an infection.

Unrecognized concept of DFU

5. Glycosylation of wound bed Collagen

In hyperglycemic patients, Glycosylation of the newly formed wound bed Collagen hinders the normal enzymatic (lysyl oxidase) maturation leading to non-healing. The hyperglycemic glucose may be absorbed by Surgicoll-Mesh® for faster healing of the ulcer wound.


Clinical Documentation Vault

Review or download comprehensive specifications, product literature, and peer-reviewed publications.

Surgicoll-Mesh® Available Sizes

Choose from our wide range of standard sizes (in cm). Custom sizes available on request.